Novel topical rosacea drug sails through phase III

WAIKOLOA, HAWAII – Ivermectin 1% cream for the treatment of papulopustular rosacea convincingly hit all of its primary efficacy and safety endpoints in two pivotal phase III clinical trials. The studies included 1,371 subjects randomized...

Topical treatments for psoriasis: Molecules to watch

Though it’s been more than a decade since a new class of topical medication has been approved for psoriasis, there are several promising new anti-inflammatory compounds to keep an eye on, says Dr. Linda Stein...

Options exist for psoriasis patients with multiple anti-TNF failures

LAS VEGAS – The use of an alternative anti–tumor necrosis factor drug is not necessarily precluded in a psoriasis patient with both skin and joint symptoms who has failed two previous anti-TNF drugs, according to...

Treatment options expand for pulmonary arterial hypertension in scleroderma

LAS VEGAS – Scleroderma patients are at particularly high risk for developing pulmonary arterial hypertension, but treatment options are expanding, and with early referral to a PAH specialist, outcomes can be improved, according to Dr. Ronald...

Most data reassure regarding TNF inhibitors and cancer

LAS VEGAS – Concerns about use of a tumor necrosis factor inhibitor in a rheumatoid arthritis patient with a history of cancer are common, but the data are largely reassuring, according to Dr. Iain McInnes...

Lupus treatment: Get back to basics

LAS VEGAS – The future looks bright for lupus treatment given the extensive list of drugs and targets currently undergoing evaluation, but for now treatment remains largely an art, according to Dr. Richard Furie. "We...

Autoantibodies play role in myositis classification, treatment

LAS VEGAS – Autoantibodies and autoantibody subsets can be particularly helpful for classifying and treating patients with myositis, including those with myositis-associated interstitial lung disease, according to Dr. Chester V. Oddis. Many autoantibody subsets are...

Limited data support multiple myositis treatment options

LAS VEGAS – Corticosteroids remain the initial treatment of choice for myositis and myositis-associated interstitial lung disease, but immunosuppressive agents, intravenous immunoglobulin, and biologics can also play a role in the treatment of one or...

No. 1 comorbidity in psoriasis is depression

MAUI, HAWAII – The cardiovascular comorbidity associated with psoriasis has drawn much attention, yet depression is arguably an even more important psoriatic comorbid condition. "I think the most important comorbidity of psoriasis is depression. We...

Topical genetic modulation therapy makes inroads

For genetic skin diseases, the future is nearly here. "It seems like every other day there’s another article published based on using next-generation gene sequencing to find out what’s causing disease, and then using that...

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