• non-CME/CE •

MAY 1 - 5, 2020

Babson Executive Conference Center
Wellesley, Massachusetts, USA

Agenda

Friday, May 1, 2020

Arrival and Registration

 

19:00 – 20:00

 

Dinner

 

Saturday, May 2, 2020

7:00 – 8:00

 

Breakfast

8:00 – 8:05

 

Welcome and Introduction
Alan Michelson (Boston, USA)

8:05 – 10:05

 

Session 1: Platelet Production I

• Molecular triggers of platelet production
Joseph Italiano (Boston, USA)

• Taking the brakes off platelet production: targeting the inhibitory receptor G6b-B
Yotis Senis (Birmingham, UK)

• Rap1 signaling in platelet production and clearance
Wolfgang Bergmeier (Chapel Hill, USA)

   

Oral Abstract Presenter
Oral Abstract Presenter

10:05 – 10:30

 

Coffee Break

10:30 – 12:30

 

Session 2: Platelet Production II

• The role of glycans in thrombopoiesis
Karin Hoffmeister (Milwaukee, USA)

• New insights into protein endocytosis during megakaryopoiesis: new ways to make platelet-targeted therapeutics
Mortimer Poncz (Philadelphia, USA)

• Manufacture of megakaryocytes and platelets from adult fat
Yumiko Matsubara (Tokyo, Japan)

   

Oral Abstract Presenter
Oral Abstract Presenter

12:30 – 16:00

 

Lunch and Free Time

16:00 – 18:00

 

Session 3: Genetics

• The 100,000 genomes project: lessons learned
Willem Ouwehand (Cambridge, UK)

• Genetic variation regulating platelet and megakaryocyte function
Paul Bray (Salt Lake City, USA)

• Digging deeper into genomes for bleeding and platelet disorders
Kathleen Freson (Leuven, Belgium)

   

Oral Abstract Presenter
Oral Abstract Presenter

18:00 – 19:30

 

Dinner

19:30 – 21:00

 

Poster Session 1

 

Sunday, May 3, 2020

7:00- 8:00

 

Breakfast

8:00 – 10:00

 

Session 4: Platelet Receptors

• Mechanosensing by the GPIb-IX complex
Renhao Li (Atlanta, USA)

• Platelet receptor ectodomains: key roles in thrombo-inflammation
Bernhard Nieswandt (Wurzburg, Germany)

• Activation of platelets by tyrosine kinase-linked glycoprotein receptors
Steve Watson (Birmingham, UK)

   

Oral Abstract Presenter
Oral Abstract Presenter

10:00- 10:30

 

Coffee Break

10:30 – 12:30

 

Session 5: Platelet Activation

• Vascular thiol isomerases in platelet activation and thrombus formation
Robert Flaumenhaft (Boston, USA)

• Metabolic regulation of platelet functions and clinic application
Junling Liu (Shanghai, China)

• Do platelets catalyze the contact activation pathway of coagulation?
Owen McCarty (Portland, USA)

   

Oral Abstract Presenter
Oral Abstract Presenter

12:30 – 16:00

 

Lunch and Free Time

16:00 – 18:00

 

Session 6: Platelet Function: the Big Picture

• Platelet function at population scale: challenges and findings
Andrew Johnson (Framingham, USA)

• Systems approach to understanding hemostasis
Lawrence “Skip” Brass (Philadelphia, USA)

• Next generation microfluidic systems to investigate platelet physiology and function
Wilbur Lam (Atlanta, USA)

   

Oral Abstract Presenter
Oral Abstract Presenter

18:00 – 19:30

 

Dinner

19:30 – 21:00

 

Poster Session 2

 

Monday, May 4, 2020

7:00 – 8:00

 

Breakfast

8:00 – 10:00

 

Session 7: The Role of Platelets in Inflammation

• Novel platelet functions during inflammatory stress
Matthew Rondina (Salt Lake City, USA)

• Platelets in lung inflammation and injury
Mark Looney (San Francisco, USA)

• Platelets/NETs in disease
Denisa Wagner (Boston, USA)

   

Oral Abstract Presenter
Oral Abstract Presenter

10:00 – 10:30

 

Coffee Break

10:30 – 12:30

 

Session 8: Platelet Function in Disease

• Role of platelets in systemic lupus erythematosus
Eric Boilard (Québec, Canada)

• Platelet biomarkers of the sudden Infant death syndrome (SIDS)
Alan Michelson (Boston, USA)

• Inherited platelet function disorders
Marco Cattaneo (Milan, Italy)

   

Oral Abstract Presenter
Oral Abstract Presenter

12:30 – 16:00

 

Lunch and Free Time

16:00 – 18:00

 

Session 9: Immune Thrombocytopenia

• Immune thrombocytopenia and immune dysregulation: the link between immunity and bleeding
Michele Lambert (Philadelphia, USA)

• Innovative therapies for ITP
David Kuter (Boston, USA)

• Heparin-induced thrombocytopenia
Andreas Greinacher (Greifswald, Germany)

   

Oral Abstract Presenter
Oral Abstract Presenter

18:00 – 19:30

 

Dinner

19:30 – 22:00

 

Farewell Reception

 

Tuesday, May 5, 2020

7:00 – 8:00

 

Breakfast

8:00 – 10:00

 

Session 10: Neonatal Thrombocytopenia

• An authentic (sort of) murine model of neonatal alloimmune thrombocytopenia
Peter Newman (Milwaukee, USA)

• Fetal and neonatal thrombocytopenia: a changing landscape
James Bussel (New York, USA)

• Platelet transfusions in neonates: the good, the bad and the ugly
Martha Sola-Visner (Boston, USA)

   

Oral Abstract Presenter
Oral Abstract Presenter

10:00 – 10:30

 

Coffee Break

10:30 – 12:30

 

Session 11: Novel Antiplatelet Therapy

• RUC-4 for first point of contact therapy of STEMI
Barry Coller (New York, USA)

• Class II PI3-kinase inhibition as an approach to widen the therapeutic window of antiplatelet therapy
Justin Hamilton (Melbourne, Australia)

• Novel mechanisms and potential new anti-platelet therapies against thrombotic diseases
Heyu Ni (Toronto, Canada)

   

Oral Abstract Presenter
Oral Abstract Presenter

12:30 – 12:35

 

Concluding Remarks
David Varon, MD (Jerusalem, Israel)

12:35

 

Lunch & Departure

     

 

 

 

 

 

The conference logo of an activated platelet is a scanning electron micrograph generously provided by John W. Weisel, Chandrasekaran Nagaswami, and Rustem I. Litvinov of the University of Pennsylvania.