Seasonal Influenza Pre-Test Questions 1. Of the 185 influenza-associated pediatric deaths during the 2017-2018 influenza season, approximately what percentage occurred in children who had not received an influenza vaccination that season? * A. 20% B. 40% C. 60% D. 80% 2. A 33-year-old pregnant woman presents at your urgent care clinic having experienced influenza symptoms for the last 72 hours. You just ran out of flu tests, but your findings on history and physical are highly suggestive of influenza and not indicative of other diagnoses. Based on CDC recommendations, you should: * A. Not offer her influenza antiviral medication because you can’t confirm her diagnosis B. Not offer her influenza antiviral medication because she is pregnant C. Not offer her influenza antiviral medication because more than 48 hours have passed since onset of symptoms D. Offer her influenza antiviral medication because her pregnancy puts her at elevated risk for influenza complications 3. All of the following are factors associated with higher intended adherence to antiviral therapy for influenza at the time of prescription except: * A. Cost B. Female sex C. Older age D. Perceived personal consequences of influenza 4. Available oral and inhaled neuraminidase inhibitors have been shown to shorten duration of influenza symptoms by roughly one-half day. Which of the following statements concerning these therapies is correct? * A. Influenza A strains often are resistant to these therapies B. These therapies have engendered relatively little viral resistance C. These therapies are not indicated for chemoprophylaxis of influenza D. These therapies are not effective against influenza B strains 5. Which of the following represents the mechanism of action of baloxavir marboxil, the most recently approved antiviral therapy for influenza? * A. Cleavage of respiratory-tract sialic acid receptors B. Inhibition of cap-dependent endonuclease of influenza A and B C. Inhibition of hemagglutinin (HA) receptor binding sites D. Inhibition of matrix 2 (M2)