Test Your Knowledge on Residual and Treatment-Emergent Symptoms in Major Depressive Disorder - Pretest

1. What is your highest attained credential? *

Other, please specify:

2. What is your specialty? *

Psychiatry

Primary Care

Research

Other, please specify:

3. What are the most common reasons for discontinuation of antidepressants in patients with major depressive disorder (MDD)? *

a. Insomnia and loss of appetite

b. Lack of efficacy and continued symptoms

c. Sexual dysfunction and weight gain

d. Difficulty concentrating and memory loss

4. Cognitive symptoms persist in up to _______ of patients with MDD during periods of remission *

a. 14%

b. 24%

c. 34%

d. 44%

Your patient is a 57-year-old woman who was diagnosed with MDD six months ago and began therapy with a selective serotonin reuptake inhibitor. Her mood has improved significantly but she is having difficulty at work and home concentrating, remembering important events, and making decisions.

5. Which of the following would be most appropriate for assessing this patient’s cognitive functioning? *

a. Mini-Mental State Examination (MMSE)

b. Massachusetts General Hospital Cognitive and Physical Functioning Questionnaire (CPFQ)

c. Patient Health Questionnaire (PHQ-9)

d. Hamilton Depression Rating Scale (HAM-D17)

Your patient is a 28-year-old man referred to you for depression. His adherence to his current regimen of a serotonin-norepinephrine reuptake inhibitor (SNRI) is poor. When asked, he reports that his current antidepressant causes “sex life problems” and that he often skips doses, including on most weekends.

6. Which of the following would you be most likely to recommend for this patient’s sexual side effects? *