Consider drug holidays for BCC patients on hedgehog inhibitors

KAUAI, HAWAII – Side effects can become intolerable after a few months, so physicians have looked for alternative dosing regimens.

Colorectal cancer threatens younger people

The rate of colorectal cancer diagnosis has risen in younger patients, with later-stage tumors predominant, according to findings from a study based on the large National Cancer Database. Over a 10-year period, the number of...

Metabolic factors associated with pancreatic NETs

SAN DIEGO – Diabetes (not recent onset), obesity, and gallstone disease were associated with the occurrence of sporadic pancreatic neuroendocrine tumors (PNET) in the prospective, case-control European EpiNet study. Cigarette smoking, first-degree family history of...

Race predicts poor outcomes in people with liver cancer

Black patients with hepatocellular carcinoma (HCC) have shorter survival and more adverse clinical features at diagnosis than do non-Hispanic whites and other races, according to a single-center review. Blacks were at a 33% increased risk...

Proactive endocrine screening urged for pediatric brain tumor survivors

BOSTON – More than a third of 419 children treated for brain tumors at Cincinnati Children’s Hospital Medical Center later developed endocrine problems, according to a review presented at the Endocrine Society annual meeting. Over...

When toenail onychomycosis can turn deadly

WAIKOLOA, HAWAII – Toenail onychomycosis is a common condition in the general population, but it’s three- to fourfold more prevalent in certain at risk populations where it can have serious and even life-threatening consequences, Dr...

Registry shows no increased cancer risk with biologics for psoriasis

WAIKOLOA, HAWAII – The latest update from the ongoing PSOLAR registry provides “very reassuring” evidence that the use of biologic agents to treat moderate to severe psoriasis doesn’t significantly increase malignancy risk other than for...

Elevated liver cancer risk after HCV cure may justify surveillance

SAN FRANCISCO – The risk of hepatocellular carcinoma remains sufficiently high in some subgroups who have achieved sustained virologic response to treatment to justify continued cancer surveillance, according to findings from a large cohort study...

Most data reassure regarding TNF inhibitors and cancer

LAS VEGAS – Concerns about use of a tumor necrosis factor inhibitor in a rheumatoid arthritis patient with a history of cancer are common, but the data are largely reassuring, according to Dr. Iain McInnes...

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